RNA has attracted considerable attention as a promising and novel target for drug discovery because of its versatile functions and its involvement in various diseases. Our focus is to develop small molecules that specifically target RNA in order to modulate its structure and function. We are actively involved in molecular design of these small molecules, leveraging the power of information science and machine learning to advance RNA-targeted chemoinformatics.
We also employ small molecules that have the ability to specifically bind to particular RNA sequences or structures, allowing us to modulate biological processes in cells that are associated with RNA.
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The Main Research Topics
Exploring and developing small molecules that can bind to RNA and applying them to biological reactions.
Developing methods to identify target RNA motifs for small molecule binding.
Analyzing the mechanism of interaction between RNA and small molecules.